Abstract: Aiming at exploring the adaptability and cultivation approach of Sorghum bicolor "JinTian No. 1" (JINTIAN) in irrigated desert oasis of Hexi Corridor,we conducted a field experiment with different irrigations (4-8 times,600 t·hm^-2 before sowing,1 200 t·hm^-2·time^-1 during growing season) and fertilizations(150 kg·hm^-2 urea as basal fertilizer at seedling stage,and the low-,medium-and high-rates of fertilizer,i.e. 225,450,675 kg·hm^-2 of N-P₂O₅-K₂O during other growing stages) to investigate an optimal irrigation-fertilization approach,and access the effects of cultivation modules (mulching on flat ground and furrow mulching) and sowing patterns (one plant·hole^-1,2 plants·hole^-1and 3 plants·hole^-1) on the plant growth,biomass,sugar content of stalk,seed yield and quality of JinTian. The results showed that JinTian was with strong adaptability to sandy wasteland. The treatment with irrigation at 7 800 t·hm^-2 (600 t·hm^-2 before sowing and 7 200 t·hm^-2 during growing period) and fertilization rate at 600 kg·hm^-2 (150 kg·hm^-2 urea at seedling stage,450 kg·hm^-2 compound fertilizer during other growing stages) was the optimal water-fertilizer coupling condition for high yield of JinTian mulched with plastic film on flat land,by which the fresh and dry weight of aboveground biomass reached 80.7 t·hm^-2 and 28.2 t·hm^-2,respectively. The content of soluble sugar in stem increased by more than 30% and the seed yield reached 2 053 kg·hm^-2,respectively. The irrigation threshold for the whole growth period of JinTian was 4 800 t·hm^-2 in irrigation regions of Hexi Corridor,and the high or low water combined with fertilizer application was not practicable to the improvement of biomass and seed yield. With the optimal water-fertilizer coupling condition,the reasonable tillage and planting methods benefited more to the biomass,stem sugar content and seed yield of sweet sorghum.Compared with mulching on flat ground,furrow mulching had more obvious effects on high yield and high quality.Based on the optimal water-fertilizer coupling condition,the planting patterns of 2 plant·hole^-1,1 plant·hole^-1 was recommended for harvesting stems,seeds while 1 plant·hole^-1 was recommended for both stem and seed harvest in sweet sorghum with mulching on flat ground (plant spacing:23 cm;row spacing:40 cm).With furrow mulching (plant spacing:23 cm;ridge width:30 cm;ridge height:25 cm),the planting modes of 2 plant·hole^-1,1 plant·hole^-1 and 1 plant·hole^-1would be recommended for the above respective harvests. The mulching on flat ground and furrow mulching high-yielding cultivation approaches would be extensively applied in irrigated desert oasis of Hexi Corridor.