Abstract: Cercospora leaf spot(CLS) is the most destructive foliar disease of sugar beet at present.For screening high-efficiency germicide,the field trial for the germicide against Cercospora leaf spot of sugar beet was conducted in Hailun region in 2011.The results showed that control efficacy of 4 species of germicide against CLS disease was different,the effect of sugar beet yield and sugar content in tuberous root wasn't significantly different and sugar beet yield was increased a little.Especially,the efficacy of Shigao in which the content of difenoconazole is 10% for controlling of CLS disease reached to 74.1%,sugar beet yield was increased by 12.4% and sugar brix in tuberous root was enhanced by 2°.The CLS disease at the initial stage was controlled by spraying Shigao twice in late July and early August with an interval of 7d.The phenomena of phytotoxicity didn't occur in field and leaves of sugar beet grew well.Therefore,Shigao was the best germicide against CLS disease in 4 species of germicide in the locality.